Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50045889
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  500nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088291(CHEMBL3427770)
Affinity DataIC50:  800nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088342(CHEMBL3427744)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088296(CHEMBL3427759)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088291(CHEMBL3427770)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088300(CHEMBL3427752)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088292(CHEMBL3427768)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088294(CHEMBL3427761)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088331(CHEMBL3427750)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088293(CHEMBL3427762)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088295(CHEMBL3427760)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088296(CHEMBL3427759)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088299(CHEMBL3427754)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50178769((+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-c...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088292(CHEMBL3427768)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088293(CHEMBL3427762)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088294(CHEMBL3427761)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088295(CHEMBL3427760)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088298(CHEMBL3427758)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of His-tagged human recombinant SIRT1 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50088297(CHEMBL3427748)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of His-tagged human recombinant SIRT2 expressed in Escherichia coli using Cbz-Lys(Ac)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed