TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.420nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.490nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.610nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.720nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.980nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 168nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 286nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 342nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 348nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: 429nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Medical University Of Lodz
Curated by ChEMBL
Medical University Of Lodz
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 4.80nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in CHO cells co-expressing Galphaq66Di5 assessed as stimulation of calcium rele...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 457nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in CHO cells co-expressing Galphaq66Di5 assessed as stimulation of calcium rele...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in CHO cells co-expressing Galphaq66Di5 assessed as stimulation of calcium rele...More data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells co-expressing C-terminally modified Galphaqi5 assessed as stimulat...More data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Agonist activity at human recombinant delta opioid receptor expressed in CHO cells co-expressing Galphaq66Di5 assessed as stimulation of calcium rele...More data for this Ligand-Target Pair