Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50046163
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant BtkMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant ALK2 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant TNK2 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant LIMK1 by LanthaScreen Binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant BmxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant BlkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant FgrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant FrkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  54nMAssay Description:Inhibition of human recombinant LynBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant TecMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  67nMAssay Description:Inhibition of human recombinant SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  82nMAssay Description:Inhibition of human recombinant LynAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  99nMAssay Description:Inhibition of human recombinant HckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  320nMAssay Description:Inhibition of human recombinant ItkMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  412nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097394(CHEMBL3586446)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097398(CHEMBL449216 | HTS-9026)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097395(CHEMBL3586445)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097394(CHEMBL3586446)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097397(CHEMBL3586443)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097398(CHEMBL449216 | HTS-9026)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097397(CHEMBL3586443)
Affinity DataIC50:  2.40E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097395(CHEMBL3586445)
Affinity DataIC50:  8.50E+5nMAssay Description:Inhibition of BTK in human Raji cells after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097394(CHEMBL3586446)
Affinity DataEC50:  92nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097393(CHEMBL3586447)
Affinity DataEC50:  28nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097397(CHEMBL3586443)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50097396(CHEMBL3586444)
Affinity DataEC50:  2.86E+4nMAssay Description:Inhibition of BTK autophosphorylation in human Raji cells after 30 mins by Phos-Y223 Btk HTRF assayMore data for this Ligand-Target Pair