Found 17 Enz. Inhib. hit(s) with all data for entry = 50046139 TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of human PTP1B catalytic domain expressed in Escherichia coli assessed as pNPP hydrolysis measured every 30 secs for 15 minsMore data for this Ligand-Target Pair
3D Structure (crystal)TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 203nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 204nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 309nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 537nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 756nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 5.19E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 9.08E+3nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of SHP2 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair
