Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with all data for entry = 50046456
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50:  190nMAssay Description:Inhibition of tryptase (unknown origin) using t-Boc-Phe-Ser-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-Arg-pNA.HCl as substrate after 5 mins by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences

Curated by ChEMBL
LigandPNGBDBM50322033(2-Methylisoindole-1,3-dione-5-yl 3-(6-aminopyridin...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of thrombin (unknown origin) using t-Boc-Val-Pro-Arg-MCA as substrate after 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed