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Found 71 Enz. Inhib. hit(s) with all data for entry = 50046297
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  14nMAssay Description:Inhibition of porcine spleen ADAM17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  772nMAssay Description:Inhibition of human MT1-MMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50203527((6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of ADAM17 in human A549 cells assessed as potentiation of gefitinib-mediated inhibition of cell viability by measuring gefitinib IC50 at 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104622(CHEMBL3593550)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of ADAM17 in human A549 cells assessed as potentiation of gefitinib-mediated inhibition of cell viability by measuring gefitinib IC50 at 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104622(CHEMBL3593550)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104620(CHEMBL3593551)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104621(CHEMBL3235911)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104631(CHEMBL3593541)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104623(CHEMBL3593549)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104624(CHEMBL3593548)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104633(CHEMBL3593361)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104628(CHEMBL3593544)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104629(CHEMBL3593543)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104627(CHEMBL3593545)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104625(CHEMBL3593547)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104630(CHEMBL3593542)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104637(CHEMBL3593357)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104638(CHEMBL3593356)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104619(CHEMBL3235912)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104626(CHEMBL3593546)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104634(CHEMBL3593360)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104620(CHEMBL3593551)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of ADAM17 in human THP1 cells assessed as inhibition of LPS-stimulated TNFalpha cleavage after 1 hr by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104636(CHEMBL3593358)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104632(CHEMBL3593362)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104635(CHEMBL3593359)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibition of ADAM17 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104621(CHEMBL3235911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104624(CHEMBL3593548)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104625(CHEMBL3593547)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104626(CHEMBL3593546)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104627(CHEMBL3593545)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104628(CHEMBL3593544)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104629(CHEMBL3593543)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104630(CHEMBL3593542)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104631(CHEMBL3593541)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104632(CHEMBL3593362)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104633(CHEMBL3593361)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104634(CHEMBL3593360)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104635(CHEMBL3593359)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104636(CHEMBL3593358)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104637(CHEMBL3593357)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104638(CHEMBL3593356)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104622(CHEMBL3593550)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of ADAM17 in human THP1 cells assessed as inhibition of LPS-stimulated TNFalpha cleavage after 1 hr by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104620(CHEMBL3593551)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 (unknown origin) preincubated for 30 mins followed by substrate addition measured every 30 mins for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104618(CHEMBL3593552)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104619(CHEMBL3235912)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104620(CHEMBL3593551)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104621(CHEMBL3235911)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Florida Atlantic University

Curated by ChEMBL
LigandPNGBDBM50104622(CHEMBL3593550)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP14 (unknown origin) using Mca-KLPGL-Dnp-AR as substrate preincubated for 30 mins followed by substrate addition measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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