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Found 14 Enz. Inhib. hit(s) with all data for entry = 50046507
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM22113((3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-y...)
Affinity DataKi:  0.00200nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate assessed as inhibition...More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM22113((3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-y...)
Affinity DataKi:  0.0480nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM22113((3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-y...)
Affinity DataKi:  0.0780nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM22113((3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-y...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50116357(CHEMBL3604360)
Affinity DataKi:  4.5nMAssay Description:Inhibition of recombinant Escherichia coli MTAN expressed in Escherichia coli BL-21 DE3 using methylthioadenosine as substrate by xanthine oxidase co...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  84nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  93nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50116358(CHEMBL3604359)
Affinity DataKi:  298nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Victoria University Of Wellington

Curated by ChEMBL
LigandPNGBDBM50116357(CHEMBL3604360)
Affinity DataKi:  750nMAssay Description:Inhibition of human MTAP using methylthioadenosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed