Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50046563
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  21nMAssay Description:Inhibition of HDAC3 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  25nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  25nMAssay Description:Inhibition of HDAC11 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  31nMAssay Description:Inhibition of HDAC10 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  130nMAssay Description:Inhibition of HDAC3 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  150nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  170nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC11 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  240nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  430nMAssay Description:Inhibition of HDAC10 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  980nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014161(CHEMBL3260858 | US11491146, Compound 5)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  2.70E+5nMAssay Description:Inhibition of HDAC1 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50014160(CHEMBL3260857)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119287(CHEMBL3617543)
Affinity DataIC50:  7.10E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed