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Found 20 Enz. Inhib. hit(s) with all data for entry = 50046647
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50013078(CHEMBL3623261)
Affinity DataEC50:  4.90E+4nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50119353(CHEMBL3623277)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50018914(CHEMBL3623263)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50049751(CHEMBL3623264)
Affinity DataEC50:  9.32E+4nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50445298(CHEMBL3104229)
Affinity DataEC50:  2.77E+4nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50049752(CHEMBL3623265)
Affinity DataEC50:  3.03E+4nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50049755(CHEMBL3623266)
Affinity DataEC50:  1.01E+4nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50049758(CHEMBL3623267)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50081726(CHEMBL3623268)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50081727(CHEMBL3623269)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50095648(CHEMBL3623270)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50095650(CHEMBL3623271)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50114770(CHEMBL3623272)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50114772(CHEMBL3623273)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50332532((E)-5-(3,4,5-trimethoxybenzylidene)imidazolidine-2...)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50115810(CHEMBL139899)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50119350(CHEMBL3623274)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50119351(CHEMBL3623275)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50119352(CHEMBL3623276)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50018912(CHEMBL3623262)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed