Compile Data Set for Download or QSAR
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Found 25 Enz. Inhib. hit(s) with all data for entry = 50046701
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human PDGFRbeta by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human CDK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human Src kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human AurA kinase by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human Akt1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human ROCK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  22nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human MEK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human FAK by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human RAF1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERK1 by kinase inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126847(CHEMBL3628537)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126846(CHEMBL481789)
Affinity DataIC50:  4.72E+3nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50126850(CHEMBL3628818)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126851(CHEMBL3628536)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM4810((3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126845(CHEMBL3628814)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126848(CHEMBL3628816)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126852(CHEMBL3628817)
Affinity DataIC50:  2.16E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126850(CHEMBL3628818)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126853(CHEMBL3628815)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126849(CHEMBL3628813)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126854(CHEMBL3628812)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126848(CHEMBL3628816)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50126852(CHEMBL3628817)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human KDR incubated for 50 mins by omnia tyr peptide 8 substrate based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed