Found 66 Enz. Inhib. hit(s) with all data for entry = 50046506 TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 162nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 216nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 219nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 407nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 525nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 562nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 617nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 870nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 977nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
University Of Eastern Finland
Curated by ChEMBL
University Of Eastern Finland
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins befor...More data for this Ligand-Target Pair
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of human MAGL expressed in HEK293 cells pre-incubated for 10 mins before 2-AG substrate addition by HPLC methodMore data for this Ligand-Target Pair
