TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Competitive inhibition of rat recombinant PDE10A by scintillation proximity assay in presence of cAMPMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET a...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PDE2A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET as...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PDE2A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET as...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PDE2A using cAMP as substrate preincubated for 20 mins followed by substrate addition measured after 2 hrs by FRET as...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 3.24E+5nMAssay Description:Binding affinity to human recombinant PDE10A after 15 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 8.51E+5nMAssay Description:Binding affinity to human recombinant PDE10A after 15 mins by surface plasmon resonance assayMore data for this Ligand-Target Pair