Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 7150
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  25.0nM IC50:  26.6nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  40.8nM IC50:  110nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataKi:  53.0nM IC50:  141nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178048((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  228nM IC50:  599nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178056(1,2,4-tribromo-3-{[2-(2,5-dibromo-3,4-dimethoxyphe...)
Affinity DataKi:  313nM IC50:  275nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178048((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  366nM IC50:  740nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178053(4-[2-(3,4-Dimethoxybenzyl)cyclopentyl]-1,2-dimetho...)
Affinity DataKi:  421nM IC50:  560nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178058((3,4-dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  455nM IC50:  514nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178057(1-[3,6a-Bis(3,4-dimethoxyphenyl)-4,5,6,6a-tetrahyd...)
Affinity DataKi:  492nM IC50:  564nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178056(1,2,4-tribromo-3-{[2-(2,5-dibromo-3,4-dimethoxyphe...)
Affinity DataKi:  510nM IC50:  475nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178049((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  561nM IC50:  422nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178055([2-(4,5-dimethoxy-2-nitrophenyl)cyclopent-1-en-1-y...)
Affinity DataKi:  573nM IC50:  854nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178059((3,4-dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  588nM IC50:  390nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178057(1-[3,6a-Bis(3,4-dimethoxyphenyl)-4,5,6,6a-tetrahyd...)
Affinity DataKi:  606nM IC50:  441nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178052((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  610nM IC50:  472nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178059((3,4-dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  616nM IC50:  395nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178050((3,4-dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  656nM IC50:  602nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178054((4,5-dimethoxy-2-nitrophenyl)[2-(4,5-dimethoxy-2-n...)
Affinity DataKi:  690nM IC50:  648nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178049((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  735nM IC50:  624nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178046(1,6-bis(3,4-dimethoxyphenyl)hexane-1,6-diol (9))
Affinity DataKi:  779nM IC50:  625nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178045(1,6-bis(3,4-dimethoxyphenyl)hexane-1,6-dione (8))
Affinity DataKi:  841nM IC50:  434nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178054((4,5-dimethoxy-2-nitrophenyl)[2-(4,5-dimethoxy-2-n...)
Affinity DataKi:  849nM IC50:  527nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178045(1,6-bis(3,4-dimethoxyphenyl)hexane-1,6-dione (8))
Affinity DataKi:  903nM IC50:  346nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178053(4-[2-(3,4-Dimethoxybenzyl)cyclopentyl]-1,2-dimetho...)
Affinity DataKi:  1.03E+3nM IC50:  504nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178047(1,6-bis(4,5-dimethoxy-2-nitrophenyl)hexane-1,6-dio...)
Affinity DataKi:  1.26E+3nM IC50:  543nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178047(1,6-bis(4,5-dimethoxy-2-nitrophenyl)hexane-1,6-dio...)
Affinity DataKi:  1.34E+3nM IC50:  395nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178051(1,2-phenylene diacetate (15))
Affinity DataKi:  1.54E+3nM IC50:  815nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178050((3,4-dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  1.54E+3nM IC50:  518nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178058((3,4-dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  1.55E+3nM IC50:  506nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178055([2-(4,5-dimethoxy-2-nitrophenyl)cyclopent-1-en-1-y...)
Affinity DataKi:  1.58E+3nM IC50:  578nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  1.69E+3nM IC50:  1.58E+3nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178052((3,4-Dimethoxyphenyl)[2-(3,4-dimethoxyphenyl)cyclo...)
Affinity DataKi:  1.79E+3nM IC50:  656nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178051(1,2-phenylene diacetate (15))
Affinity DataKi:  1.81E+3nM IC50:  736nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Atat£Rk University

LigandPNGBDBM178046(1,6-bis(3,4-dimethoxyphenyl)hexane-1,6-diol (9))
Affinity DataKi:  1.93E+3nM IC50:  697nMAssay Description:CA isoenzymes activities were determined in according to the method of Verpoorte et al. (76) described previously (77). The increasing in absorbance ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed