Compile Data Set for Download or QSAR
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Found 52 Enz. Inhib. hit(s) with all data for entry = 50047362
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162283(CHEMBL3793576)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162285(CHEMBL3792819)
Affinity DataIC50:  30nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162274(CHEMBL3793091)
Affinity DataIC50:  58nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162293(CHEMBL3794417)
Affinity DataIC50:  83nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162290(CHEMBL3793904)
Affinity DataIC50:  87nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162276(CHEMBL3794430)
Affinity DataIC50:  88nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162283(CHEMBL3793576)
Affinity DataIC50:  95nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50:  109nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162285(CHEMBL3792819)
Affinity DataIC50:  121nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162292(CHEMBL3792515)
Affinity DataIC50:  180nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162290(CHEMBL3793904)
Affinity DataIC50:  214nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162273(CHEMBL3792996)
Affinity DataIC50:  223nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162289(CHEMBL3793941)
Affinity DataIC50:  253nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162274(CHEMBL3793091)
Affinity DataIC50:  317nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162286(CHEMBL3793139)
Affinity DataIC50:  327nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162291(CHEMBL3794161)
Affinity DataIC50:  372nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162289(CHEMBL3793941)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162292(CHEMBL3792515)
Affinity DataIC50:  522nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162275(CHEMBL3794391)
Affinity DataIC50:  612nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162286(CHEMBL3793139)
Affinity DataIC50:  620nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162293(CHEMBL3794417)
Affinity DataIC50:  643nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162291(CHEMBL3794161)
Affinity DataIC50:  768nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162276(CHEMBL3794430)
Affinity DataIC50:  954nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162273(CHEMBL3792996)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162288(CHEMBL3794457)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162288(CHEMBL3794457)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162283(CHEMBL3793576)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162275(CHEMBL3794391)
Affinity DataIC50:  3.27E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162272(CHEMBL3794177)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162276(CHEMBL3794430)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162272(CHEMBL3794177)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162274(CHEMBL3793091)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162276(CHEMBL3794430)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162274(CHEMBL3793091)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162277(CHEMBL3794438)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162293(CHEMBL3794417)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human placental CYP19 using [1beta-3H]-androstenedione as substrate for 3 hrs measured as formation of [3]H2O in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162293(CHEMBL3794417)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162284(CHEMBL3793530)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162278(CHEMBL3792680)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162279(CHEMBL3792398)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162280(CHEMBL3794567)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162281(CHEMBL3793057)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162282(CHEMBL3792868)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B2 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 30 mins by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162283(CHEMBL3793576)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli co-transfected with rat NADPH-P450 reductase using progesterone as substrate for 30 mins meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162277(CHEMBL3794438)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162278(CHEMBL3792680)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162279(CHEMBL3792398)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM50162280(CHEMBL3794567)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP11B1 expressed in V79 MZh cells using [1,2-3H]-11-deoxycorticosterone as substrate for 6 hrs by HPTLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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