Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 7182
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM60588(3-(3-fluoro-4-{[2-(pyridin-3-yl)-1H-pyrrolo[2,3-b]...)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM60589(6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...)
Affinity DataIC50:  4nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  7.67nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM60587(3-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50:  11nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM60590(6-(1-{6-phenyl-[1,2,4]triazolo[4,3-b][1,2,4]triazi...)
Affinity DataIC50:  13nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  13.7nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179803(3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...)
Affinity DataIC50:  14.6nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  17.3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179803(3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...)
Affinity DataIC50:  17.6nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50:  22.8nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179802(3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...)
Affinity DataIC50:  47.4nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179804(3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...)
Affinity DataIC50:  51.2nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179800(3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...)
Affinity DataIC50:  63nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM60586(4-(4-{3-[1-(2,6-dichloro-3-fluorophenyl)ethyl]-1H-...)
Affinity DataIC50: <100nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179803(3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...)
Affinity DataIC50:  133nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50:  135nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50:  188nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179800(3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...)
Affinity DataIC50:  214nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179798(3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...)
Affinity DataIC50:  286nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179803(3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...)
Affinity DataIC50:  337nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179804(3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...)
Affinity DataIC50:  372nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179798(3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...)
Affinity DataIC50:  504nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179802(3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...)
Affinity DataIC50:  508nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50:  578nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50:  651nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179800(3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...)
Affinity DataIC50:  725nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179802(3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...)
Affinity DataIC50:  735nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform 2 of Hepatocyte growth factor receptor (2)(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179799(4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...)
Affinity DataIC50:  982nMpH: 7.0 T: 2°CAssay Description:The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179800(3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...)
Affinity DataIC50:  1.31E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179798(3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...)
Affinity DataIC50:  1.52E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179798(3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...)
Affinity DataIC50:  1.66E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179804(3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...)
Affinity DataIC50:  2.10E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179799(4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...)
Affinity DataIC50:  2.71E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179804(3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...)
Affinity DataIC50:  2.81E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179802(3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...)
Affinity DataIC50:  2.99E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179799(4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...)
Affinity DataIC50:  3.31E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor [C1156Y](Homo sapiens (Human))
Tianjin University Of Science And Technology

LigandPNGBDBM179799(4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...)
Affinity DataIC50:  4.08E+3nMpH: 7.5 T: 2°CAssay Description:The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed