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Found 8 Enz. Inhib. hit(s) with all data for entry = 50047328
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50352142(CHEMBL1824770)
Affinity DataIC50:  430nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50160597(CHEMBL3787397)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50090067(6,6-Dimethyl-1-phenyl-1,6-dihydro-[1,3,5]triazine-...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50160596(CHEMBL3785981)
Affinity DataIC50:  5.64E+4nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50160595(CHEMBL3787681)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM29143(CHEMBL7976 | Chalcone 1 | Chalcone, 13 | cid_63776...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50160594(CHEMBL3785320)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant dihydrofolate reductase using dihydrofolate as substrate measured every 30 secs over 6 mins by UV/visible spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed