Affinity DataKi: 58nMAssay Description:Binding affinity to human EP4More data for this Ligand-Target Pair
Affinity DataKi: >1.40E+4nMAssay Description:Binding affinity to human EP3More data for this Ligand-Target Pair
Affinity DataKi: >1.75E+4nMAssay Description:Binding affinity to human EP1More data for this Ligand-Target Pair
Affinity DataKi: >1.89E+4nMAssay Description:Binding affinity to human EP2More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity against rat EP4 assessed as inhibition of PGE2-stimulated production of cAMPMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Antagonist activity against human EP4 expressed in HEK293 cells assessed as inhibition of PGE2-stimulated production of cAMP incubated for 20 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.89E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair