Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50047531
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173375(CHEMBL3810248)
Affinity DataIC50:  59nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173495(CHEMBL3809404)
Affinity DataIC50:  102nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173487(CHEMBL3809360)
Affinity DataIC50:  123nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173488(CHEMBL3810234)
Affinity DataIC50:  166nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173372(CHEMBL3808867)
Affinity DataIC50:  182nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173336(CHEMBL3808645)
Affinity DataIC50:  211nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173494(CHEMBL3810347 | US11629146, Compound 108)
Affinity DataIC50:  223nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173339(CHEMBL3809838)
Affinity DataIC50:  281nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173134(CHEMBL3809595)
Affinity DataIC50:  333nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173492(CHEMBL3809528)
Affinity DataIC50:  351nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173496(CHEMBL3809853)
Affinity DataIC50:  353nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173407(CHEMBL3809777)
Affinity DataIC50:  397nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173502(CHEMBL3809904)
Affinity DataIC50:  417nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173501(CHEMBL3809080)
Affinity DataIC50:  425nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173338(CHEMBL3808917)
Affinity DataIC50:  887nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173500(CHEMBL3810153)
Affinity DataIC50:  901nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173493(CHEMBL3809877)
Affinity DataIC50:  941nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173498(CHEMBL3808625)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173489(CHEMBL3808737)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173340(CHEMBL3809812)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173497(CHEMBL3808489)
Affinity DataIC50:  3.35E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173499(CHEMBL3808581)
Affinity DataIC50:  5.05E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-gated sodium channel Nav1.5 cardiac isoform(Canis lupus familiaris)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173335(CHEBI:87690 | CVT-303 | RS-43285-003 | Ranexa | Ra...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of canine ventricular myocytes Nav 1.5 assessed as reduction in ATX-2 induced late channel current by manual single-patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173490(CHEMBL3809933)
Affinity DataIC50:  7.54E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173337(CHEMBL3808631)
Affinity DataIC50:  7.92E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50173491(CHEMBL3810266)
Affinity DataIC50:  8.94E+3nMAssay Description:Inhibition of Nav 1.5 (unknown origin) assessed as reduction in late channel currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed