Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 50047597
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  2nMAssay Description:Competitive inhibition of FLT3 ITD mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  2nMAssay Description:Inhibition of FLT3 ITD mutant in human MOLM13 cells assessed as reduction in cell viability a after 3 days by cell titer glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)
Affinity DataIC50:  3nMAssay Description:Competitive inhibition of FLT3 ITD mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  4nMAssay Description:Competitive inhibition of FLT3 D835Y mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)
Affinity DataIC50:  4nMAssay Description:Competitive inhibition of FLT3 D835Y mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  4nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  5nMAssay Description:Competitive inhibition of FLT3 D835Y mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177779(CHEMBL3814908)
Affinity DataIC50:  6nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  10nMAssay Description:Competitive inhibition of FLT3 ITD mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  11nMAssay Description:Inhibition of FLT3 ITD mutant in human MOLM14 cells assessed as reduction in cell viability after 3 days by cell titer glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177721(CHEMBL3814657)
Affinity DataIC50:  14nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177779(CHEMBL3814908)
Affinity DataIC50:  18nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177721(CHEMBL3814657)
Affinity DataIC50:  26nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177723(CHEMBL3814446)
Affinity DataIC50:  31nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177723(CHEMBL3814446)
Affinity DataIC50:  33nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177776(CHEMBL3814462)
Affinity DataIC50:  34nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177718(CHEMBL3814734)
Affinity DataIC50:  40nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177776(CHEMBL3814462)
Affinity DataIC50:  55nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177719(CHEMBL3814055)
Affinity DataIC50:  62nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177718(CHEMBL3814734)
Affinity DataIC50:  74nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  78nMAssay Description:Inhibition of PHKGI (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177720(CHEMBL3814090)
Affinity DataIC50:  83nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)
Affinity DataIC50:  93nMAssay Description:Competitive inhibition of FLT3 D835Y mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177724(CHEMBL3814032)
Affinity DataIC50:  96nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177717(CHEMBL3814207)
Affinity DataIC50:  96nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177720(CHEMBL3814090)
Affinity DataIC50:  97nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177725(CHEMBL3815134)
Affinity DataIC50:  114nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177725(CHEMBL3815134)
Affinity DataIC50:  124nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177775(CHEMBL3814654)
Affinity DataIC50:  126nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177717(CHEMBL3814207)
Affinity DataIC50:  128nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50:  130nMAssay Description:Competitive inhibition of FLT3 ITD mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  142nMAssay Description:Inhibition of CLK4 (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177724(CHEMBL3814032)
Affinity DataIC50:  143nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177719(CHEMBL3814055)
Affinity DataIC50:  146nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177775(CHEMBL3814654)
Affinity DataIC50:  182nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177726(CHEMBL3813745)
Affinity DataIC50:  280nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177773(CHEMBL3813913)
Affinity DataIC50:  356nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177726(CHEMBL3813745)
Affinity DataIC50:  365nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177722(CHEMBL3814702)
Affinity DataIC50:  424nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177722(CHEMBL3814702)
Affinity DataIC50:  430nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177773(CHEMBL3813913)
Affinity DataIC50:  502nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177772(CHEMBL3814677)
Affinity DataIC50:  692nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177715(CHEMBL3815054)
Affinity DataIC50:  936nMAssay Description:Inhibition of ROCK2 (unknown origin) by kinomescan analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177772(CHEMBL3814677)
Affinity DataIC50:  937nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177774(CHEMBL3814749)
Affinity DataIC50:  946nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177777(CHEMBL3813943)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177770(CHEMBL3815101)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177774(CHEMBL3814749)
Affinity DataIC50:  2.24E+3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50177777(CHEMBL3813943)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) transduced in mouse Ba/F3 cells assessed as reduction in cell viability after 3 days by cell titer glo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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