Found 8 Enz. Inhib. hit(s) with all data for entry = 50048047 TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of FLAP in human monocytes assessed as suppression of fMLP/LPS-stimulated cys-LT formation preincubated for 15 mins measured after 10 mins...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of FLAP in human monocytes assessed as suppression of A23187-stimulated 5-LO product formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of FLAP in human monocytes assessed as suppression of A23187-stimulated 5-LO product formation using 10 uM arachidonic acid as substrate p...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Gazi University
Curated by ChEMBL
Gazi University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of FLAP in human neutrophils assessed as suppression of A23187-stimulated 5-LO product formation using arachidonic acid as substrate prein...More data for this Ligand-Target Pair
