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Found 24 Enz. Inhib. hit(s) with all data for entry = 50048159
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50129964(1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50112086(3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-met...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50038001((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206816(CHEMBL3907547)
Affinity DataIC50:  83nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206818(CHEMBL3969770)
Affinity DataIC50:  147nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206800(CHEMBL3922260)
Affinity DataIC50:  437nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206815(CHEMBL3950003)
Affinity DataIC50:  446nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206809(CHEMBL3913261)
Affinity DataIC50:  456nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206799(CHEMBL3958679)
Affinity DataIC50:  511nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50432209(BIBR-1048 | BIBR-1048-BS-RS1 | DABIGATRAN ETEXILAT...)
Affinity DataIC50:  554nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206810(CHEMBL3931186)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206801(CHEMBL3977163)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206803(CHEMBL3964811)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206813(CHEMBL3978841)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of human thrombin assessed as reduction in release of free nitroaniline using tosyl-glycyl-prolyl-arginine-4-nitranilide acetate as substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206802(CHEMBL3935798)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206798(CHEMBL3960020)
Affinity DataIC50:  8.16E+3nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206808(CHEMBL3909953)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206805(CHEMBL3979276)
Affinity DataIC50:  8.82E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206811(CHEMBL3971094)
Affinity DataIC50:  9.12E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206814(CHEMBL3899919)
Affinity DataIC50:  9.15E+4nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206806(CHEMBL3889895)
Affinity DataIC50:  1.64E+5nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206804(CHEMBL3961893)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206807(CHEMBL3890936)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombin(Oryctolagus cuniculus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50206812(CHEMBL3908646)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of rabbit thrombin-induced platelet aggregation in rabbit platelet-rich plasma preincubated with rabbit liver microsomes for 4 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed