Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50049014
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus-infected insect cells using Luciferin-1A2 as substrate in presence of NADPH by P450-Glo luminesce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cells using Luciferin-ME EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus-infected insect cells using Luciferin-H EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of human ERG by Tracer Red dye based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50:  2.48E+4nMAssay Description:Inhibition of human CYP2D6 expressed in baculovirus-infected insect cells using Luciferin-ME EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50:  2.74E+4nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus-infected insect cells using Luciferin-PFBE as substrate in presence of NADPH by P450-Glo luminesc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50:  4.21E+4nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus-infected insect cells using Luciferin-H as substrate in presence of NADPH by P450-Glo luminescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 expressed in baculovirus-infected insect cells using Luciferin-PFBE as substrate in presence of NADPH by P450-Glo luminesc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C9 expressed in baculovirus-infected insect cells using Luciferin-H as substrate in presence of NADPH by P450-Glo luminescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 expressed in baculovirus-infected insect cells using Luciferin-1A2 as substrate in presence of NADPH by P450-Glo luminesce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50232898(CHEMBL4071093)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERG by Tracer Red dye based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Modena And Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM45440(4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19 expressed in baculovirus-infected insect cells using Luciferin-H EGE as substrate in presence of NADPH by P450-Glo lumine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank