TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Negative allosteric modulation of mGlu5 receptor (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Negative allosteric modulation of recombinant human mGlu5a receptor assessed as inhibition of quisqualate-stimulated phosphoinositide hydrolysis by c...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Negative allosteric modulation of human mGlu5a receptor expressed in HEK293 cells co-expressing EAAC1 assessed as inhibition of quisqualate-induced i...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 1.21E+3nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 3.09E+3nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 4.92E+3nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Institute For Advanced Chemistry Of Catalonia (Iqac-Csic)
Curated by ChEMBL
Affinity DataIC50: 6.13E+3nMAssay Description:Negative allosteric modulation of rat N-terminal HA-tagged mGlu5 receptor expressed in HEK293 cells co-expressing N-terminal HA-tagged EAAC1 assessed...More data for this Ligand-Target Pair