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Found 6 Enz. Inhib. hit(s) with all data for entry = 50049170
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of The Ministry Of Education For Medicinal Resources And Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of The Ministry Of Education For Medicinal Resources And Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235600(CHEMBL3542268)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of The Ministry Of Education For Medicinal Resources And Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235601(CHEMBL4089347)
Affinity DataIC50:  16nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of The Ministry Of Education For Medicinal Resources And Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235598(CHEMBL4066845)
Affinity DataIC50:  24nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of The Ministry Of Education For Medicinal Resources And Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  27nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Key Laboratory Of The Ministry Of Education For Medicinal Resources And Natural Pharmaceutical Chemistry

Curated by ChEMBL
LigandPNGBDBM50235599(CHEMBL4088135)
Affinity DataIC50:  34nMAssay Description:Inhibition of wild type recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed