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Found 38 Enz. Inhib. hit(s) with all data for entry = 50049230
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237034(CHEMBL4061626)
Affinity DataKi:  12nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237035(CHEMBL4099881)
Affinity DataKi:  13nMAssay Description:Inhibition of human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237046(CHEMBL4103288)
Affinity DataKi:  25nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237014(CHEMBL4099341)
Affinity DataKi:  27nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease (isolated domain)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237013(CHEMBL4061015)
Affinity DataKi:  30nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease (isolated domain)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237011(CHEMBL4094982)
Affinity DataKi:  77nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237021(CHEMBL4069851)
Affinity DataKi:  77nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237012(CHEMBL4082899)
Affinity DataKi:  91nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237015(CHEMBL4063816)
Affinity DataKi:  123nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237009(CHEMBL4085357)
Affinity DataKi:  167nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237045(CHEMBL4073007)
Affinity DataKi:  200nMAssay Description:Inhibition of human Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237041(CHEMBL4067188)
Affinity DataKi:  217nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237028(CHEMBL4078113)
Affinity DataKi:  279nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237016(CHEMBL4091604)
Affinity DataKi:  304nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237037(CHEMBL4101829)
Affinity DataKi:  358nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237018(CHEMBL4074742)
Affinity DataKi:  411nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease (full-length)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237025(CHEMBL4093759)
Affinity DataKi:  505nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237029(CHEMBL4097098)
Affinity DataKi:  515nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237020(CHEMBL4098566)
Affinity DataKi:  671nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease (full-length)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237031(CHEMBL4086930)
Affinity DataKi:  952nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237027(CHEMBL4094638)
Affinity DataKi:  1.01E+3nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237022(CHEMBL4096129)
Affinity DataKi:  1.02E+3nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237010(CHEMBL4067563)
Affinity DataKi:  1.43E+3nMAssay Description:Inhibitory activity against hepatitis C virus (HCV) NS3 protease (isolated domain)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237036(CHEMBL4072407)
Affinity DataKi:  1.75E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237044(CHEMBL4075354)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237024(CHEMBL4060177)
Affinity DataKi:  2.79E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237033(CHEMBL4083435)
Affinity DataKi:  3.02E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237030(CHEMBL4104808)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237026(CHEMBL4073055)
Affinity DataKi:  3.86E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237039(CHEMBL4090845)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237023(CHEMBL4068832)
Affinity DataKi: >5.10E+3nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237017(CHEMBL4083827)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237042(CHEMBL4102383)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237043(CHEMBL4079078)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibitory concentration against Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase (GAPDH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237038(CHEMBL4095211)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237019(CHEMBL4080539)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of human Cathepsin L by fluorescence assay based Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237032(CHEMBL4070294)
Affinity DataKi: >5.10E+3nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Roche Pharmaceutical Research And Early Development (Pred)

Curated by ChEMBL
LigandPNGBDBM50237040(CHEMBL4088405)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibitory concentration against Trypanosoma mexicana glyceraldehyde-3-phosphate dehydrogenase (GAPDH)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed