Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 50002108
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020287(7-[2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6...)
Affinity DataIC50:  1nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020291(3-Hydroxy-5-oxo-7-phenyl-heptanoic acid | CHEMBL60...)
Affinity DataIC50:  1.30nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020290(7-[2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6...)
Affinity DataIC50:  1.60nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020288(3,5-Dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-bu...)
Affinity DataIC50:  13nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020293(3-Hydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-butyry...)
Affinity DataIC50:  32nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020292(3-Hydroxy-7-[2-(2-methyl-butyryloxymethyl)-phenyl]...)
Affinity DataIC50:  3.20E+5nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
University Of California

Curated by ChEMBL
LigandPNGBDBM50020289(3,5-Dihydroxy-7-phenyl-heptanoic acid | CHEMBL5941...)
Affinity DataIC50:  6.00E+5nMAssay Description:Ability of compound to inhibit the activity of 3-hydroxy-3-methylglutarylcoenzyme A(HMGR) reductase in rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed