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Found 13 Enz. Inhib. hit(s) with all data for entry = 50001201
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271977(CHEMBL4127558)
Affinity DataEC50: >100nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271983(CHEMBL4128655)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271984(CHEMBL4128688)
Affinity DataEC50:  68nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271985(CHEMBL4126485)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271986(CHEMBL4129882)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271987(CHEMBL4126607)
Affinity DataEC50: >100nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50161834(CHEMBL3794175)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271996(CHEMBL4130175)
Affinity DataEC50: >1.00E+3nMAssay Description:Non-competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using ploy(dA)/oligo(dT)18 as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271997(CHEMBL4128816)
Affinity DataEC50:  95nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271998(CHEMBL4127302)
Affinity DataEC50:  2.30nMAssay Description:Inhibition of human DNA polymerase delta assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50272007(CHEMBL4127444)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50272009(CHEMBL4126062)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human TGR5 expressed in CHOK1 cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50271995(CHEMBL4130025)
Affinity DataEC50:  22nMAssay Description:Competitive inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli using dTTP as substrate by Dixon plot analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed