Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50002413
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022130(3-(2-Cyclopropyl-3-imidazol-1-ylmethyl-indol-1-yl)...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022118(3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022117(1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022131(3-(3-Imidazol-1-ylmethyl-6-trifluoromethyl-indol-1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022129(3-(5-Bromo-3-imidazol-1-ylmethyl-indol-1-yl)-propi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50:  15nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50:  19nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022119(3-(5-Chloro-3-imidazol-1-ylmethyl-indol-1-yl)-prop...)
Affinity DataIC50:  21nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50:  25nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50:  28nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50:  30nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022127(3-(3-Imidazol-1-ylmethyl-5-methyl-indol-1-yl)-prop...)
Affinity DataIC50:  42nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022122(3-(3-Imidazol-1-ylmethyl-5-methoxy-indol-1-yl)-pro...)
Affinity DataIC50:  43nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022123(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-acry...)
Affinity DataIC50:  70nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022125(3-(5-Dimethylamino-3-imidazol-1-ylmethyl-indol-1-y...)
Affinity DataIC50:  82nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022132(5-Chloro-3-imidazol-1-ylmethyl-1H-indole | CHEMBL1...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022128(3-Imidazol-1-ylmethyl-6-trifluoromethyl-1H-indole ...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of TXA2 synthetase from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022118(3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022117(1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022118(3-(3-Imidazol-1-ylmethyl-2-isopropyl-indol-1-yl)-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022127(3-(3-Imidazol-1-ylmethyl-5-methyl-indol-1-yl)-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022131(3-(3-Imidazol-1-ylmethyl-6-trifluoromethyl-indol-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022125(3-(5-Dimethylamino-3-imidazol-1-ylmethyl-indol-1-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022122(3-(3-Imidazol-1-ylmethyl-5-methoxy-indol-1-yl)-pro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022119(3-(5-Chloro-3-imidazol-1-ylmethyl-indol-1-yl)-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 11 beta-hydroxylase from rat adrenal glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM7962(4-(2-Imidazol-1-yl-ethoxy)-benzoic acid; hydrochlo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022117(1-Ethyl-3-imidazol-1-ylmethyl-1H-indole | CHEMBL11...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022126((3-Imidazol-1-ylmethyl-indol-1-yl)-acetic acid | C...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022121(3-Imidazol-1-ylmethyl-2-isopropyl-1H-indole | 3-Im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50000317(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-prop...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022124(3-(3-Imidazol-1-ylmethyl-indol-1-yl)-propionic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022123(3-(3-Imidazol-1-ylmethyl-2-methyl-indol-1-yl)-acry...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022130(3-(2-Cyclopropyl-3-imidazol-1-ylmethyl-indol-1-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022129(3-(5-Bromo-3-imidazol-1-ylmethyl-indol-1-yl)-propi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50:  6.50E+5nMAssay Description:Inhibition of PGI-2 synthetase from porcine aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50022120(3-Imidazol-1-ylmethyl-1H-indole | CHEMBL116794)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Prostaglandin G/H synthase from ram seminal vesicle microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed