Found 60 Enz. Inhib. hit(s) with all data for entry = 50009109 TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Mus musculus)
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse VEGFR-2 (785 to 1376 residues)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDGFR beta (561 to 1106 residues) (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of GST-tagged TIE2 (unknown origin) using biotin-Ahx-EPKDDAYPLYSDFG peptide as substrate by HTRF methodMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Mus musculus (mouse))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of mouse VEGFR-3 (818 to 1363 residues)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of PDGFR beta (unknown origin)More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of RAF1 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 440nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human wild type BRAF by Kinase-Glo luminescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Research Centre
Curated by ChEMBL
National Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human N-terminal GST tagged VEGFR-2 expressed in baculovirus infected Sf9 cells using poly (Glu,Tyr) 4:1 as substrate in presence of AT...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of TIE2 (unknown origin)More data for this Ligand-Target Pair
