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PubMed code 32150407

Compile data set for download or QSAR
Found 27 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-lactamase OXA-23


(Acinetobacter baumannii)
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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0.740n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Acinetobacter baumannii OXA-23 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every 10 ...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Carbapenem-hydrolyzing beta-lactamase KPC


()
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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1.90n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-lactamase VIM-1


(Klebsiella pneumoniae)
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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8n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli VIM-1 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Carbapenem-hydrolyzing beta-lactamase KPC


()
BDBM50339145
PNG
(CHEMBL1689063 | trans-7-oxo-6-(sulfooxy)-1,6-diaza...)
Show SMILES NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O
Show InChI InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
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11n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Carbapenem-hydrolyzing beta-lactamase KPC


()
BDBM50541449
PNG
(CHEMBL4636953)
Show SMILES Nc1nnc(SCC(=O)N[C@H]2Cc3cccc(C(O)=O)c3OB2O)s1
Show InChI InChI=1S/C13H13BN4O5S2/c15-12-17-18-13(25-12)24-5-9(19)16-8-4-6-2-1-3-7(11(20)21)10(6)23-14(8)22/h1-3,8,22H,4-5H2,(H2,15,17)(H,16,19)(H,20,21)/t8-/m0/s1
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21n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Carbapenem-hydrolyzing beta-lactamase KPC


()
BDBM50089084
PNG
(CHEMBL3317857 | Vaborbactam)
Show SMILES OB1O[C@H](CC(O)=O)CC[C@@H]1NC(=O)Cc1cccs1
Show InChI InChI=1S/C12H16BNO5S/c15-11(7-9-2-1-5-20-9)14-10-4-3-8(6-12(16)17)19-13(10)18/h1-2,5,8,10,18H,3-4,6-7H2,(H,14,15)(H,16,17)/t8-,10-/m0/s1
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56n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbapenem-hydrolyzing beta-lactamase KPC


()
BDBM50541450
PNG
(CHEMBL4640702)
Show SMILES OB1Oc2c(C[C@@H]1Sc1nncs1)cccc2C(O)=O
Show InChI InChI=1S/C11H9BN2O4S2/c15-10(16)7-3-1-2-6-4-8(12(17)18-9(6)7)20-11-14-13-5-19-11/h1-3,5,8,17H,4H2,(H,15,16)/t8-/m0/s1
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150n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli KPC-2 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition and measured e...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Beta-lactamase OXA-23


(Acinetobacter baumannii)
BDBM50339145
PNG
(CHEMBL1689063 | trans-7-oxo-6-(sulfooxy)-1,6-diaza...)
Show SMILES NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O
Show InChI InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
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1.70E+3n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Acinetobacter baumannii OXA-23 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every 10 ...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Beta-lactamase VIM-1


(Klebsiella pneumoniae)
BDBM50339145
PNG
(CHEMBL1689063 | trans-7-oxo-6-(sulfooxy)-1,6-diaza...)
Show SMILES NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(O)(=O)=O
Show InChI InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
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>4.00E+4n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli VIM-1 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Beta-lactamase OXA-23


(Acinetobacter baumannii)
BDBM50089084
PNG
(CHEMBL3317857 | Vaborbactam)
Show SMILES OB1O[C@H](CC(O)=O)CC[C@@H]1NC(=O)Cc1cccs1
Show InChI InChI=1S/C12H16BNO5S/c15-11(7-9-2-1-5-20-9)14-10-4-3-8(6-12(16)17)19-13(10)18/h1-2,5,8,10,18H,3-4,6-7H2,(H,14,15)(H,16,17)/t8-,10-/m0/s1
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>4.00E+4n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of Acinetobacter baumannii OXA-23 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every 10 ...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Beta-lactamase VIM-1


(Klebsiella pneumoniae)
BDBM50089084
PNG
(CHEMBL3317857 | Vaborbactam)
Show SMILES OB1O[C@H](CC(O)=O)CC[C@@H]1NC(=O)Cc1cccs1
Show InChI InChI=1S/C12H16BNO5S/c15-11(7-9-2-1-5-20-9)14-10-4-3-8(6-12(16)17)19-13(10)18/h1-2,5,8,10,18H,3-4,6-7H2,(H,14,15)(H,16,17)/t8-,10-/m0/s1
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>4.00E+4n/an/an/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant Escherichia coli VIM-1 using nitrocefin as substrate preincubated for 10 mins followed by substrate addition measured every...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Catalase


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a 1.10E+3n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian cathepsin A (unknown origin) using MCA-RPPGFSAFK-Dnp as substrate preincubated for 10 mins followed by substrate addition mea...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian thrombin (unknown origin) using Benz-FVR-AMC as substrate preincubated for 10 mins followed by substrate addition measured af...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Leukocyte elastase


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a 1.32E+5n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian neutrophil elastase (unknown origin) using MeOSuc-AAVP-AMC as substrate preincubated for 10 mins followed by substrate additi...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Endothelin-converting enzyme 1


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a 4.31E+5n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian ECE-1 (unknown origin) using MCA-RPPGFSAFK(DNP)-OH as substrate preincubated for 10 mins followed by substrate addition measu...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Cathepsin G


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a 6.66E+5n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian cathepsin G (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Chymase


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian chymase (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measured aft...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 9


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian DPP9 (unknown origin) using Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 3...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian DPP7 (unknown origin) using H-Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Trypsin


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian trypsin (unknown origin) using N-Bz-R-AMC as substrate preincubated for 10 mins followed by substrate addition measured after...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Chymotrypsinogen B2


(Homo sapiens)
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian chymotrypsin (unknown origin) using Suc-AAPF-AMC as substrate preincubated for 10 mins followed by substrate addition measure...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Angiotensin-converting enzyme 2


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian ACE-2 (unknown origin) using Mca-APK(Dnp) as substrate preincubated for 10 mins followed by substrate addition measured after...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Matrix metalloproteinase-9


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian MMP-9 (unknown origin) using McaPLGLDpaAR-NH2 as substrate preincubated for 10 mins followed by substrate addition measured a...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator/surface receptor


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian urokinase (unknown origin) using NGK-pNA as substrate preincubated for 10 mins followed by substrate addition measured after ...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Interstitial collagenase


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian MMP-1 (unknown origin) using McaPLGLDpaAR-NH2 as substrate preincubated for 10 mins followed by substrate addition measured a...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Plasminogen


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian plasmin (unknown origin) using H-D-VLK-pNA as substrate preincubated for 10 mins followed by substrate addition measured afte...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 8/9


(Homo sapiens (Human))
BDBM50541448
PNG
(CHEMBL4633785)
Show SMILES OB1Oc2c(ccc(F)c2C(O)=O)[C@H]2C[C@@H]12
Show InChI InChI=1S/C10H8BFO4/c12-7-2-1-4-5-3-6(5)11(15)16-9(4)8(7)10(13)14/h1-2,5-6,15H,3H2,(H,13,14)/t5-,6-/m1/s1
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n/an/a>1.00E+6n/an/an/an/an/an/a



Qpex Biopharma, Inc.

Curated by ChEMBL


Assay Description
Inhibition of mammalian DPP8 (unknown origin) using Lys-Pro-AMC as substrate preincubated for 10 mins followed by substrate addition measured after 3...


J Med Chem 63: 7491-7507 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01976
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%