Affinity DataKi: 44nMAssay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Inhibition constant for Tyr31-dihydrofolate reductase (DHFR)-NADPH-Compound complexMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 9.5More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nM ΔG°: -32.1kJ/molepH: 5.5 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKi: 9.10E+3nMAssay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+5nMAssay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKon: 25M-1s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 490nMpH: 8.5Assay Description:Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 810nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 4.40E+3nMpH: 7.0Assay Description:Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 6.20E+3nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKon: 12M-1s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKd: 2.60E+3nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKoff: 1.20E+7s-1Assay Description:Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKoff: 1.10E+7s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 340nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 210nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 140nMpH: 8.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 0.0960nMpH: 8.0Assay Description:Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKd: 3.90E+3nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKon: 26M-1s-1Assay Description:Binding constant(Ki) to dihydrofolate reductase (DHFR) Phe -31 was determinedMore data for this Ligand-Target Pair
Affinity DataKd: 31nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 0.0230nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 240nMpH: 8.5Assay Description:Dissociation constant at Val-31(Kon)of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKoff: 6.80E+6s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 400nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKoff: 1.50E+5s-1Assay Description:Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 9.5More data for this Ligand-Target Pair
Affinity DataKd: 220nMpH: 7.0Assay Description:Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 300nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8.5More data for this Ligand-Target Pair
Affinity DataKd: 60nMpH: 7.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 380nMpH: 7.0Assay Description:Association constant at Val-31(Kon) of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKon: 35M-1s-1Assay Description:Binding constant(Ki) to dihydrofolate reductase (DHFR) Val -31 was determinedMore data for this Ligand-Target Pair
Affinity DataKd: 84nMpH: 8.0Assay Description:Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKon: 26M-1s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8More data for this Ligand-Target Pair
Affinity DataKoff: 3.60E+7s-1Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 2.30nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 3.20nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 300nMpH: 8.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 6.60E+3nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 4.80E+3nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 300nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair