Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50011656
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(Maleimide-Related Compound 13 | pyrrolidine-2,5-di...)
Affinity DataKi:  642nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549803(ABT-333 | CHEBI:85182 | Dasabuvir | Dasabuvir sodi...)
Affinity DataKi:  4.71E+3nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataKi:  4.94E+3nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(Maleimide-Related Compound 13 | pyrrolidine-2,5-di...)
Affinity DataKi:  8.19E+3nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
Affinity DataKi:  8.51E+3nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence in pr...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM65456(19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.07E+4nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataKi:  1.63E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM76986(3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...)
Affinity DataKi:  1.67E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549802(CHEMBL1258836)
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549802(CHEMBL1258836)
Affinity DataKi:  2.70E+4nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549810(CHEMBL4797970)
Affinity DataKi:  3.08E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549811(CHEMBL4759876)
Affinity DataKi:  4.07E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549806(CHEMBL4758352)
Affinity DataKi:  6.78E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi:  1.02E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.37E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50207238(Thiohydantoin)
Affinity DataKi:  1.69E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549809(BMS-205603-01 | CHEBI:17568 | Fluorouracil specifi...)
Affinity DataKi:  2.12E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549804(CHEBI:27612 | Hydantoin | Imidazolidine-2,4-Dione)
Affinity DataKi:  2.16E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549807(CHEMBL4756680)
Affinity DataKi:  2.29E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50088517(CHEBI:16704 | Uridine)
Affinity DataKi:  3.90E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  5.70E+6nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform by FRET assayMore data for this Ligand-Target Pair
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.10E+7nMAssay Description:Competitive binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST ba...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataKi:  1.37E+8nMAssay Description:Competitive binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(Maleimide-Related Compound 13 | pyrrolidine-2,5-di...)
Affinity DataIC50:  3.53E+3nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549803(ABT-333 | CHEBI:85182 | Dasabuvir | Dasabuvir sodi...)
Affinity DataIC50:  1.56E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM65497(CC-220 (Compound 6) | US9694015, 6.4S)
Affinity DataIC50:  1.60E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataIC50:  2.08E+4nMAssay Description:Binding affinity to Magnetospirillum gryphiswaldense cereblon isoform 4 by measuring baseline corrected normalized fluorescence by MST based assayMore data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM7814(Maleimide-Related Compound 13 | pyrrolidine-2,5-di...)
Affinity DataIC50:  2.23E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50070114((+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-i...)
Affinity DataIC50:  2.29E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence in pr...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM65456(19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)is...)
Affinity DataIC50:  2.58E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM65454(191732-72-6 | CC-5013 | Lenalidomide | Revimid | R...)
Affinity DataIC50:  3.78E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM76986(3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-pipe...)
Affinity DataIC50:  3.87E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549810(CHEMBL4797970)
Affinity DataIC50:  6.57E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549811(CHEMBL4759876)
Affinity DataIC50:  8.48E+4nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549806(CHEMBL4758352)
Affinity DataIC50:  1.37E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  2.02E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50026472((CH3)2SO | (methanesulfinyl)methanedimethyl sulfox...)
Affinity DataIC50:  2.64E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50207238(Thiohydantoin)
Affinity DataIC50:  3.32E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549809(BMS-205603-01 | CHEBI:17568 | Fluorouracil specifi...)
Affinity DataIC50:  4.15E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549804(CHEBI:27612 | Hydantoin | Imidazolidine-2,4-Dione)
Affinity DataIC50:  4.21E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549807(CHEMBL4756680)
Affinity DataIC50:  4.47E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50088517(CHEBI:16704 | Uridine)
Affinity DataIC50:  7.57E+5nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549808(Akritoin | Furagin | Furaginum | Furazidin | Furaz...)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549802(CHEMBL1258836)
Affinity DataIC50: >1.00E+6nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataIC50: >5.00E+6nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein cereblon(Homo sapiens (Human))
Max Planck Institute For Developmental Biology

Curated by ChEMBL
LigandPNGBDBM50549805(CHEMBL30446 | Imidazolidin-4-One)
Affinity DataIC50: >5.00E+6nMAssay Description:Binding affinity to human CRBN-thalidomide binding domain expressed in Escherichia coli by measuring baseline corrected normalized fluorescence by MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed