Found 43 Enz. Inhib. hit(s) with all data for entry = 50012714 
Affinity DataKi: 0.300nMAssay Description:Binding affinity to recombinant human S1P5 receptor expressed in Chem-1 cell membrane by 33P-SIP binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity to recombinant human S1P5 receptor expressed in Chem-1 cell membrane by 33P-SIP binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity to recombinant human S1P5 receptor expressed in Chem-1 cell membrane by 33P-SIP binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to recombinant human S1P1 receptor expressed in Chem-1 cell membrane by 33P-SIP binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to recombinant human S1P1 receptor expressed in Chem-1 cell membrane by 33P-SIP binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 165nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 3.81E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.960nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.270nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.810nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0630nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 267nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 406nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at recombinant human S1P1 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: >5nMAssay Description:Agonist activity at recombinant human S1P2 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 27nMAssay Description:Agonist activity at recombinant human S1P3 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at recombinant human S1P4 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 602nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 67nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 1.54E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 1.24E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 236nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 0.360nMAssay Description:Agonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as calcium flux measured for 180 secs by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Antagonist activity at recombinant human S1P5 receptor expressed in Chem-1 cells assessed as EC80 S1P-induced calcium flux measured for 180 secs by F...More data for this Ligand-Target Pair
