Affinity Data by PubMed id=33799173

PubMed code 33799173

Found 12 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50459054 (CHEMBL4213248) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	<3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM50459054 (CHEMBL4213248) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	<3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM81818 (CAS_1794 \| CHEMBL1909810 \| HMA \| NSC_1794) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(nc1N)N1CCCCCC1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM50529246 (CHEMBL4473654) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50529246 (CHEMBL4473654) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM16173 (3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(N)nc1N Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50529264 (CHEMBL4513418) Show SMILES COc1ncc(cn1)-c1nc(C(=O)NC(N)=N)c(N)nc1N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM50459059 (CHEMBL4217043) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50459059 (CHEMBL4217043) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM16173 (3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(N)nc1N Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM81818 (CAS_1794 \| CHEMBL1909810 \| HMA \| NSC_1794) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(nc1N)N1CCCCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair
1,3-beta-glucan synthase component GSC2 (Saccharomyces cerevisiae)	BDBM50529264 (CHEMBL4513418) Show SMILES COc1ncc(cn1)-c1nc(C(=O)NC(N)=N)c(N)nc1N Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp method				Bioorg Med Chem 37: (2021)
University of Wollongong Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%