Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50012443
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557676(CHEMBL4763955)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557672(CHEMBL4788669)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557678(CHEMBL4754084)
Affinity DataIC50:  61nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557660(CHEMBL4783741)
Affinity DataIC50:  136nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557666(CHEMBL4786255)
Affinity DataIC50:  165nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557652(CHEMBL4793291)
Affinity DataIC50:  167nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557679(CHEMBL4793279)
Affinity DataIC50:  195nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557677(CHEMBL4750925)
Affinity DataIC50:  322nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557656(CHEMBL4783466)
Affinity DataIC50:  335nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557674(CHEMBL4795194)
Affinity DataIC50:  454nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557675(CHEMBL4743249)
Affinity DataIC50:  505nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Rattus norvegicus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  545nMAssay Description:Inhibition of recombinant rat KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557673(CHEMBL4781553)
Affinity DataIC50:  573nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  622nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557682(CHEMBL4745211)
Affinity DataIC50:  744nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557683(CHEMBL4758890)
Affinity DataIC50:  778nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557659(CHEMBL4779088)
Affinity DataIC50:  977nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557676(CHEMBL4763955)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557678(CHEMBL4754084)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557664(CHEMBL4750826)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557670(CHEMBL4744857)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557658(CHEMBL4789512)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557685(CHEMBL4750807)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557671(CHEMBL4740667)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557672(CHEMBL4788669)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557653(CHEMBL4763819)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557665(CHEMBL4777757)
Affinity DataIC50:  4.47E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557668(CHEMBL4751954)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557681(CHEMBL4776478)
Affinity DataIC50:  6.28E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557661(CHEMBL4759833)
Affinity DataIC50:  6.49E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557684(CHEMBL4744290)
Affinity DataIC50:  9.29E+3nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin) by patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557655(CHEMBL4793050)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557669(CHEMBL4755742)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of human ERG by patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalcium-activated potassium channel subunit beta-1(Homo sapiens (Human))
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of BK (unknown origin) by patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557666(CHEMBL4786255)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 2(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of KCNT2 (unknown origin) by patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557677(CHEMBL4750925)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of Iks (unknown origin) by patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557654(CHEMBL4780006)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557657(CHEMBL4781377)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557662(CHEMBL4743513)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557663(CHEMBL4753774)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Homo sapiens)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557667(CHEMBL4797412)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium channel subfamily T member 1(Mus musculus)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557679(CHEMBL4793279)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557680(CHEMBL4741793)
Affinity DataIC50:  4.20E+4nMAssay Description:Inhibition of human Nav1.5 by patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed