Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50002948
LigandPNGBDBM50024979(3-Ethoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity at pH 8.5 in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024992(3-Isopropoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]py...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity at pH 8.5 in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024980(3-But-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM46858(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of solubilized, purified rat liver HMG-CoA reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024995(3-Prop-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-...)
Affinity DataIC50:  5.80E+3nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024993(3-Ethoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of solubilized, purified rat liver HMG-CoA reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of solubilized, purified rat liver HMG-CoA reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024985(3-Allyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyri...)
Affinity DataIC50:  9.60E+3nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024990(3-Propoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024992(3-Isopropoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]py...)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024989(3-(2-Bromo-allyloxy)-4,5,6,7-tetrahydro-isoxazolo[...)
Affinity DataIC50:  1.30E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024981(3-But-2-enyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024991(5-Ethyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity at pH 8.5 in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024987(3-Butoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024989(3-(2-Bromo-allyloxy)-4,5,6,7-tetrahydro-isoxazolo[...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024996(3-Methoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024984(1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid meth...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024983(3-Benzyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50:  3.20E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity at pH 8.5 in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024990(3-Propoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50:  3.50E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024988(3-Methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024983(3-Benzyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50:  4.80E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024994(3-Isobutoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50:  4.90E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024981(3-But-2-enyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024987(3-Butoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024986(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024982(3-Hydroxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro antagonistic activity against peripheral Muscarinic acetylcholine receptor in guinea pig ileum as inhibition of acetylcholine induced muscle...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024986(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of solubilized, purified rat liver HMG-CoA reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024994(3-Isobutoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of binding of radioactive N-propylbenzilycholine mustard ([3H]-PrBCM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024982(3-Hydroxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme activity in rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024983(3-Benzyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024980(3-But-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataEC50:  4.50E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024984(1,2,5,6-Tetrahydro-pyridine-3-carboxylic acid meth...)
Affinity DataEC50:  300nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024986(5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024987(3-Butoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024985(3-Allyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyri...)
Affinity DataEC50:  1.30E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024988(3-Methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataEC50:  1.80E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataEC50:  70nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024996(3-Methoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,...)
Affinity DataEC50:  800nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024982(3-Hydroxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024992(3-Isopropoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]py...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024994(3-Isobutoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyr...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024991(5-Ethyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataEC50:  2.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024995(3-Prop-2-ynyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-...)
Affinity DataEC50:  1.20E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024979(3-Ethoxy-5-methyl-4,5,6,7-tetrahydro-isoxazolo[4,5...)
Affinity DataEC50:  1.60E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024993(3-Ethoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridi...)
Affinity DataEC50:  3.40E+3nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024989(3-(2-Bromo-allyloxy)-4,5,6,7-tetrahydro-isoxazolo[...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024981(3-But-2-enyloxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM46858(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Affinity DataEC50:  100nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024990(3-Propoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyrid...)
Affinity DataEC50: >5.00E+4nMAssay Description:Contraction of guinea pig ileum by muscarinic AChR activation, which could be inhibited by application of atropineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed