Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 239
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246811(US10053461, 2 | US10093673, Compound 1.2 | cis-10-...)
Affinity DataIC50:  1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246831(Cis-11-((6-hydroxyhexyl)oxy)-10-methoxy-3,3-dimeth...)
Affinity DataIC50:  1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246819(Cis-11-(cyclopropylmethoxy)-10-methoxy-3,3-dimethy...)
Affinity DataIC50:  1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246818(Cis-11-isobutoxy-10-methoxy-3,3-dimethyl-7-oxo-1,2...)
Affinity DataIC50:  1nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246850(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(pyrrolidin-1...)
Affinity DataIC50: <1.60nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246835(Cis-10-methoxy-3,3-dimethyl-11-((6-(methylsulfonam...)
Affinity DataIC50:  2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246829(Cis-10-methoxy-3,3-dimethyl-11-(3-(methylthio)prop...)
Affinity DataIC50:  2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246832(Cis-11-((6-((tert-butoxycarbonyl)amino)hexyl)oxy)-...)
Affinity DataIC50:  2nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246837(US10053461, 28 | cis-13-chloro-12-(3-methoxypropox...)
Affinity DataIC50:  3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246812(Cis-11-(benzyloxy)-10-methoxy-3,3-dimethyl-7-oxo-1...)
Affinity DataIC50:  3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246817(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(2,2,2-triflu...)
Affinity DataIC50:  3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246823(Cis-11-(3-hydroxy-2,2-dimethylpropoxy)-10-methoxy-...)
Affinity DataIC50:  3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246812(Cis-11-(benzyloxy)-10-methoxy-3,3-dimethyl-7-oxo-1...)
Affinity DataIC50:  3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246820(Cis-10-methoxy-11-(2-methoxyethoxy)-3,3-dimethyl-7...)
Affinity DataIC50:  4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246821(Cis-11-(3-cyanopropoxy)-10-methoxy-3,3-dimethyl-7-...)
Affinity DataIC50:  4nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246816(Cis-10,11-dimethoxy-3,3-dimethyl-7-oxo-1,2,3,3a,7,...)
Affinity DataIC50:  5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246822(Cis-11-(3-hydroxypropoxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50:  5nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246834(Cis-11-((6-acetamidohexyl)oxy)-10-methoxy-3,3-dime...)
Affinity DataIC50:  6nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246824(Cis-10-methoxy-3,3-dimethyl-11-(3-morpholinopropox...)
Affinity DataIC50:  6nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246810(US10053461, 1 | US10093673, Compound rac-2 | trans...)
Affinity DataIC50:  10nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246827(Cis-11-(4-ethoxy-4-oxobutoxy)-10-methoxy-3,3-dimet...)
Affinity DataIC50:  10nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246830(Cis-10-methoxy-3,3-dimethyl-11-(3-(methylsulfonyl)...)
Affinity DataIC50:  17nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246849(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-propyl-1,2,3,...)
Affinity DataIC50:  19nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246833(Cis-11-((6-aminohexyl)oxy)-10-methoxy-3,3-dimethyl...)
Affinity DataIC50:  20nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246848(Cis-10-methoxy-3,3,11-trimethyl-7-oxo-1,2,3,3a,7,1...)
Affinity DataIC50:  20nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246836(US10053461, 27 | trans-13-chloro-12-(3-methoxyprop...)
Affinity DataIC50:  20nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246826(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(3-(2-oxopyrr...)
Affinity DataIC50:  25nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246845(US10053461, 36 | cis-11-methoxy-12-(3-methoxypropo...)
Affinity DataIC50:  28nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246847(Cis-10-methoxy-3,3,11-trimethyl-7-oxo-1,2,3,3a,7,1...)
Affinity DataIC50:  36nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246841(US10053461, 32 | cis-12-benzyloxy-11-methoxy-8-oxo...)
Affinity DataIC50:  44nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246815(Cis-11-hydroxy-10-methoxy-3,3-dimethyl-7-oxo-1,2,3...)
Affinity DataIC50:  84nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246844(Trans-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4...)
Affinity DataIC50:  110nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246840(Trans-12-benzyloxy-11-methoxy-8-oxo-1,2,3,4,4a,13b...)
Affinity DataIC50:  120nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246825(Cis-10-methoxy-3,3-dimethyl-7-oxo-11-(3-(pyrrolidi...)
Affinity DataIC50:  128nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246838(US10053461, 29 | trans-2-((benzyloxy)carbonyl)-11-...)
Affinity DataIC50:  152nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246843(US10053461, 34 | cis-11-methoxy-12-(3-methoxypropo...)
Affinity DataIC50:  186nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246842(Trans-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4...)
Affinity DataIC50:  265nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246814((3aR,12bS)-11-(benzyloxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50:  308nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246828(Cis-11-(3-carboxypropoxy)-10-methoxy-3,3-dimethyl-...)
Affinity DataIC50:  505nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246839(US10053461, 30 | cis-2-((benzyloxy)carbonyl)-11-me...)
Affinity DataIC50:  564nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetLarge envelope protein(Hepatitis B virus)
Hoffmann-La Roche

US Patent
LigandPNGBDBM246846(Trans-11-methoxy-12-(3-methoxypropoxy)-8-oxo-1,3,4...)
Affinity DataIC50:  2.20E+3nMT: 2°CAssay Description:HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent