Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 50003258
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50024971(6-Fluoren-9-ylidenemethyl-4-hydroxy-tetrahydro-pyr...)
Affinity DataIC50:  890nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026324(6-Dibenzo[a,d]cyclohepten-5-ylidenemethyl-4-hydrox...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026319(4-Hydroxy-6-(2-phenanthren-4-yl-vinyl)-tetrahydro-...)
Affinity DataIC50:  1.90E+3nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026320(6-[2-(2,4-Dichloro-phenyl)-ethyl]-4-hydroxy-tetrah...)
Affinity DataIC50:  1.52E+4nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026321(6-[2-(2,4-Dichloro-phenyl)-ethyl]-4-hydroxy-4-meth...)
Affinity DataIC50:  1.98E+4nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026322(6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-4-meth...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026112(6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrah...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026112(6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrah...)
Affinity DataIC50:  2.20E+4nMAssay Description:Binding affinity against Dihydrofolate reductase of chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026325(6-[2-(Decahydro-naphthalen-2-yl)-ethyl]-4-hydroxy-...)
Affinity DataIC50:  9.00E+4nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026323(6-[2-(Decahydro-naphthalen-1-yl)-ethyl]-4-hydroxy-...)
Affinity DataIC50:  1.07E+5nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50014952(4-Hydroxy-6-(2-naphthalen-1-yl-ethyl)-tetrahydro-p...)
Affinity DataIC50:  1.29E+5nMAssay Description:In vitro inhibitory activity against HMG CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed