Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50004350
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482057(CHEMBL1092328)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482058(CHEMBL1091563)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482059(CHEMBL1093188)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482060(CHEMBL1089200)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482062(CHEMBL1091494)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482061(CHEMBL1089530)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482056(CHEMBL1092725)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of gamma-secretase-mediated Notch deltaE cleavage in human HeLa cells by luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed