Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50028873
LigandPNGBDBM50008064((S)-3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-ox...)
Affinity DataIC50:  43nMAssay Description:Compound was evaluated for its ability to displace muscarinic agonist [3H]quinuclidinyl benzilate in rat cortical tissue (RCMD binding assay), at 0.1...More data for this Ligand-Target Pair
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LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataIC50:  360nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
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LigandPNGBDBM50004665((oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyr...)
Affinity DataIC50:  860nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
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LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataIC50:  4.43E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
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LigandPNGBDBM50008072((+)-pilocarpine | (3S,4R)-3-ethyl-4-[(1-methyl-1H-...)
Affinity DataIC50:  8.80E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
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LigandPNGBDBM50008064((S)-3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-ox...)
Affinity DataIC50:  8.90E+3nMAssay Description:Compound was evaluated for its ability to displace muscarinic antagonist [3H]cis-methyldioxolane in rat cortical tissue (RQNB binding assay), at 1.0 ...More data for this Ligand-Target Pair
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LigandPNGBDBM46858(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Affinity DataIC50:  9.15E+3nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
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LigandPNGBDBM46858(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Affinity DataIC50:  1.19E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
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LigandPNGBDBM50008064((S)-3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-ox...)
Affinity DataIC50:  1.27E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
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LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataIC50:  1.89E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
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LigandPNGBDBM50008064((S)-3-Ethyl-4-(3-methyl-3H-imidazol-4-ylmethyl)-ox...)
Affinity DataIC50:  3.09E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)More data for this Ligand-Target Pair
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LigandPNGBDBM50004656((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)
Affinity DataIC50:  4.44E+4nMAssay Description:Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...More data for this Ligand-Target Pair
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LigandPNGBDBM50211667(CHEMBL37008)
Affinity DataIC50:  7.30E+4nMAssay Description:Compound was evaluated for its ability to displace muscarinic agonist [3H]quinuclidinyl benzilate in rat cortical tissue (RCMD binding assay), at 0.1...More data for this Ligand-Target Pair
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LigandPNGBDBM50211667(CHEMBL37008)
Affinity DataIC50:  3.30E+6nMAssay Description:Compound was evaluated for its ability to displace muscarinic antagonist [3H]cis-methyldioxolane in rat cortical tissue (RQNB binding assay), at 1.0 ...More data for this Ligand-Target Pair
In DepthDetails Article