Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50028993
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50003351(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Affinity DataIC50:  7nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50003359(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
LigandPNGBDBM50006579(5-(4-Butoxy-furazan-3-yl)-1-methyl-1,2,3,6-tetrahy...)
Affinity DataIC50:  24nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50003371(5-(4-Hexyloxy-furazan-3-yl)-1-methyl-1,2,3,6-tetra...)
Affinity DataIC50:  70nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM46858(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Affinity DataIC50:  77nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50003371(5-(4-Hexyloxy-furazan-3-yl)-1-methyl-1,2,3,6-tetra...)
Affinity DataIC50:  277nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50006579(5-(4-Butoxy-furazan-3-yl)-1-methyl-1,2,3,6-tetrahy...)
Affinity DataIC50:  345nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50006584((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...)
Affinity DataIC50:  355nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280531(5-(4-Butoxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetrah...)
Affinity DataIC50:  369nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280531(5-(4-Butoxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetrah...)
Affinity DataIC50:  477nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280532(5-(3-Butoxy-isothiazol-4-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50:  544nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280532(5-(3-Butoxy-isothiazol-4-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50:  565nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280533(5-(4-Hexyloxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50:  663nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280530(5-(3-Hexyloxy-isothiazol-4-yl)-1-methyl-1,2,3,6-te...)
Affinity DataIC50:  715nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50212579(CHEMBL167375)
Affinity DataIC50:  759nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280533(5-(4-Hexyloxy-thiophen-3-yl)-1-methyl-1,2,3,6-tetr...)
Affinity DataIC50: >900nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280530(5-(3-Hexyloxy-isothiazol-4-yl)-1-methyl-1,2,3,6-te...)
Affinity DataIC50: >900nMAssay Description:Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50006584((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...)
Affinity DataIC50:  955nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM46858(1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid...)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [3H]-Pz (pirenzepine) from the muscarinic receptor M1 of the rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails Article