Compile Data Set for Download or QSAR
maximum 50k data
Found 45 Enz. Inhib. hit(s) with all data for entry = 50028997
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280583(CHEMBL423832 | N*2*,N*2*-Diethyl-2-methyl-N*1*-(6-...)
Affinity DataKi:  112nMAssay Description:Compound was tested for its affinity for muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280609(2-[6-(1-Ethyl-pyrrolidin-2-ylamino)-4-methyl-pyrid...)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280589((+)-(1-Ethyl-pyrrolidin-2-yl)-(6-phenyl-5-propyl-p...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280589((+)-(1-Ethyl-pyrrolidin-2-yl)-(6-phenyl-5-propyl-p...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280612((1-Ethyl-pyrrolidin-2-yl)-(6-methyl-5-phenyl-pyrid...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280599(CHEMBL168670 | N*2*,N*2*-Diethyl-N*1*-(6-isobutyl-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280589((+)-(1-Ethyl-pyrrolidin-2-yl)-(6-phenyl-5-propyl-p...)
Affinity DataIC50:  30nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280587(CHEMBL167016 | N*1*-(5,6-Diphenyl-pyridazin-3-yl)-...)
Affinity DataIC50:  40nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280605(CHEMBL353869 | N*2*,N*2*-Diethyl-2-methyl-N*1*-(5-...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280617(CHEMBL169663 | N'-(6,7-Dihydro-5H-benzo[6,7]cycloh...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280583(CHEMBL423832 | N*2*,N*2*-Diethyl-2-methyl-N*1*-(6-...)
Affinity DataIC50:  110nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280582(2-[6-(2-Diethylamino-2-methyl-propylamino)-4-propy...)
Affinity DataIC50:  130nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280603(CHEMBL352419 | N,N-Dimethyl-N'-(2-methyl-biphenyl-...)
Affinity DataIC50:  140nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280616((5,6-Diphenyl-pyridazin-3-yl)-(2-morpholin-4-yl-et...)
Affinity DataIC50:  170nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280588(CHEMBL165815 | N*2*,N*2*-Diethyl-2-methyl-N*1*-(6-...)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280614(CHEMBL151705 | N,N-Dimethyl-N'-(4-methyl-6-phenyl-...)
Affinity DataIC50:  230nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280615(CHEMBL356373 | N,N-Diethyl-N'-(4-methyl-6-phenyl-p...)
Affinity DataIC50:  240nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280586(2-[6-(2-Diethylamino-2-methyl-propylamino)-4-methy...)
Affinity DataIC50:  240nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280594(CHEMBL168674 | N'-(6,7-Dihydro-5H-benzo[6,7]cycloh...)
Affinity DataIC50:  240nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280591((1-Ethyl-pyrrolidin-2-yl)-(5-methyl-6-phenyl-pyrid...)
Affinity DataIC50:  260nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280619((6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridaz...)
Affinity DataIC50:  370nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280618(CHEMBL355400 | N,N-Diethyl-N'-(6-phenyl-5-propyl-p...)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280602(CHEMBL353952 | N*1*-(5-Cyclopropyl-6-phenyl-pyrida...)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280620(CHEMBL167057 | N,N-Dimethyl-N'-(2-methyl-biphenyl-...)
Affinity DataIC50:  500nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50140766((5-Methyl-6-phenyl-pyridazin-3-yl)-(2-morpholin-4-...)
Affinity DataIC50:  550nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50074285((4,6-Diphenyl-pyridazin-3-yl)-(2-morpholin-4-yl-et...)
Affinity DataIC50:  600nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280606((4,5-Dimethyl-6-phenyl-pyridazin-3-yl)-(2-morpholi...)
Affinity DataIC50:  700nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280592((1-Ethyl-pyrrolidin-2-ylmethyl)-(4-methyl-6-phenyl...)
Affinity DataIC50:  800nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280596((4-Ethyl-6-phenyl-pyridazin-3-yl)-(2-morpholin-4-y...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280608((2-Morpholin-4-yl-ethyl)-(6-phenyl-5-propyl-pyrida...)
Affinity DataIC50:  1.60E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280593((6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridaz...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280610(CHEMBL166990 | N*2*,N*2*-Diethyl-2-methyl-N*1*-(5-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280597((4-Methyl-6-thiophen-2-yl-pyridazin-3-yl)-(2-morph...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280597((4-Methyl-6-thiophen-2-yl-pyridazin-3-yl)-(2-morph...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [3H]pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280585((4-Benzyl-6-phenyl-pyridazin-3-yl)-(2-morpholin-4-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280600((6-Cyclohexyl-4-methyl-pyridazin-3-yl)-(2-morpholi...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280584((4-Methyl-6-naphthalen-2-yl-pyridazin-3-yl)-(2-mor...)
Affinity DataIC50:  7.50E+3nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50074279((2-Morpholin-4-yl-ethyl)-(6-phenyl-pyridazin-3-yl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280601((2-Morpholin-4-yl-ethyl)-(4-naphthalen-2-ylmethyl-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50074289((4-Methyl-6-phenyl-pyridazin-3-yl)-(2-morpholin-4-...)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50074280(3-(2-Morpholin-4-yl-ethylamino)-6-phenyl-pyridazin...)
Affinity DataIC50:  6.00E+4nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280611(3-(2-Morpholin-4-yl-ethylamino)-6-phenyl-pyridazin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280613(1-[2-(4-Methyl-6-phenyl-pyridazin-3-ylamino)-ethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280595(4-[2-(4-Methyl-6-phenyl-pyridazin-3-ylamino)-ethyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280590(3-(2-Morpholin-4-yl-ethylamino)-6-phenyl-pyridazin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of [3H]-pirenzepine from cerebral Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails Article