Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50029718
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287226((S)-5-Oxo-5-[4-(3-piperidin-4-yl-propyl)-piperidin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287220((S)-5-Oxo-2-phenylmethanesulfonylamino-5-[4-(3-pip...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287231((S)-2-Benzenesulfonylamino-5-oxo-5-[4-(3-piperidin...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287219((S)-2-(Biphenyl-4-sulfonylamino)-5-oxo-5-[4-(3-pip...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287217((S)-2-(Naphthalene-2-sulfonylamino)-5-oxo-5-[4-(3-...)
Affinity DataIC50:  40nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287222((S)-2-(Naphthalene-1-sulfonylamino)-5-oxo-5-[4-(3-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287225((S)-2-(Octane-1-sulfonylamino)-5-oxo-5-[4-(3-piper...)
Affinity DataIC50:  70nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287218((S)-2-(Butane-1-sulfonylamino)-5-oxo-5-[4-(3-piper...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287221((R)-4-(Butane-1-sulfonylamino)-5-oxo-5-[4-(3-piper...)
Affinity DataIC50:  130nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287215((S)-5-Oxo-2-pentanoylamino-5-[4-(3-piperidin-4-yl-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287224(3-(Butane-1-sulfonylamino)-5-oxo-5-[4-(3-piperidin...)
Affinity DataIC50:  950nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287223(5-Oxo-5-[4-(3-piperidin-4-yl-propyl)-piperidin-1-y...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287230(6-Oxo-6-[4-(3-piperidin-4-yl-propyl)-piperidin-1-y...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287228((S)-5-Oxo-2-pentylamino-5-[4-(3-piperidin-4-yl-pro...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287227((R)-2-(Butane-1-sulfonylamino)-5-oxo-5-[4-(3-piper...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287216((S)-4-(Butane-1-sulfonylamino)-5-oxo-5-[4-(3-piper...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287229(4-Oxo-4-[4-(3-piperidin-4-yl-propyl)-piperidin-1-y...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of [125I]- Fg binding to fibrinogen receptor of activated human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article