Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50029963
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289727(4-Hydroxy-piperidine-1-carboxylic acid ((S)-1-{[(S...)
Affinity DataIC50:  0.680nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289726(1H-Benzoimidazole-2-carboxylic acid [(S)-1-((1S,2S...)
Affinity DataIC50:  13nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50:  42nMAssay Description:In vitro renin inhibitory effect of the compound was evaluated for plasma renin activity (PRA) of marmoset plasma renin, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50:  45nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289716(5-Fluoro-1H-indole-2-carboxylic acid [(S)-1-((1S,2...)
Affinity DataIC50:  46nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289724(1-Oxo-1,2-dihydro-isoquinoline-3-carboxylic acid [...)
Affinity DataIC50:  48nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50:  93nMAssay Description:In vitro renin inhibitory effect of the compound was evaluated for plasma renin activity (PRA) of dog plasma renin, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289723(Benzofuran-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-...)
Affinity DataIC50:  140nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289720(5-Chloro-1H-indole-2-carboxylic acid [(S)-1-((1S,2...)
Affinity DataIC50:  260nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289722(1-Acetyl-1H-indole-2-carboxylic acid [(S)-1-((1S,2...)
Affinity DataIC50:  340nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289721((S)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50:  420nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289718(5-Hydroxy-1H-indole-2-carboxylic acid [(S)-1-((1S,...)
Affinity DataIC50:  600nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289725(CHEMBL301306 | Isoquinoline-3-carboxylic acid [(S)...)
Affinity DataIC50:  790nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289715(1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid [(S)-1...)
Affinity DataIC50:  800nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289713(2,3-Dihydro-1H-indole-2-carboxylic acid [(S)-1-((1...)
Affinity DataIC50:  880nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289713(2,3-Dihydro-1H-indole-2-carboxylic acid [(S)-1-((1...)
Affinity DataIC50:  880nMAssay Description:In vitro renin inhibitory effect of the compound was evaluated for plasma renin activity (PRA) of monkey plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289719(1H-Pyrrole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289717(Benzo[b]thiophene-2-carboxylic acid [(S)-1-((1S,2S...)
Affinity DataIC50:  8.20E+3nMAssay Description:In vitro renin inhibitory effect was evaluated for plasma renin activity (PRA) of human plasma, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against cathepsin D (bovine), expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity of the compound against ACE human, expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetPepsin A(Porcine)
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory effect of the compound was evaluated against pepsin, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289714(1H-Indole-2-carboxylic acid [(S)-1-((1S,2S,4S)-1-c...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro renin inhibitory effect of the compound was evaluated for plasma renin activity (PRA) of rat plasma renin, Expressed as IC50More data for this Ligand-Target Pair
In DepthDetails Article