Compile Data Set for Download or QSAR
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Found 45 Enz. Inhib. hit(s) with all data for entry = 50030078
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM79215(CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...)
Affinity DataKi:  0.140nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290921(4-(5,6,7,8-Tetrahydro-naphthalen-1-yl)-piperazine-...)
Affinity DataKi:  0.5nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM79215(CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...)
Affinity DataKi:  0.700nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataKi:  0.800nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290915(4-(2,6-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataKi:  1.30nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290912(4-(2,4-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataKi:  1.80nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50173098(4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  2nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataKi:  2nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290914(4-o-Tolyl-piperazine-1-carboxylic acid [4-methoxy-...)
Affinity DataKi:  2.30nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290916(4-o-Tolyl-piperazine-1-carboxylic acid 4-chloro-3-...)
Affinity DataKi:  3.60nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataKi:  8nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290918(4-(3-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  8nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290919(4-(4-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  8.40nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi:  10nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290923(2-[4-Chloro-3-(4-methyl-piperazin-1-yl)-phenoxy]-1...)
Affinity DataKi:  11nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290922(4-Phenyl-piperazine-1-carboxylic acid [4-methoxy-3...)
Affinity DataKi:  18nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290921(4-(5,6,7,8-Tetrahydro-naphthalen-1-yl)-piperazine-...)
Affinity DataKi:  26nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290915(4-(2,6-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataKi:  37nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290913(2-[4-Methoxy-3-(4-methyl-piperazin-1-yl)-phenylami...)
Affinity DataKi:  40nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290914(4-o-Tolyl-piperazine-1-carboxylic acid [4-methoxy-...)
Affinity DataKi:  48nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290918(4-(3-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  70nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM79215(CHEMBL15928 | GR 127935 | GR 127935 hydrochloride ...)
Affinity DataKi:  72nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290918(4-(3-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  79nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290912(4-(2,4-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataKi:  88nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50173098(4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  90nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290916(4-o-Tolyl-piperazine-1-carboxylic acid 4-chloro-3-...)
Affinity DataKi:  150nMAssay Description:Affinity for 5-hydroxytryptamine 1B receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290919(4-(4-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  230nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290923(2-[4-Chloro-3-(4-methyl-piperazin-1-yl)-phenoxy]-1...)
Affinity DataKi:  240nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290921(4-(5,6,7,8-Tetrahydro-naphthalen-1-yl)-piperazine-...)
Affinity DataKi:  257nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi:  260nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290922(4-Phenyl-piperazine-1-carboxylic acid [4-methoxy-3...)
Affinity DataKi:  340nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290914(4-o-Tolyl-piperazine-1-carboxylic acid [4-methoxy-...)
Affinity DataKi:  390nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290915(4-(2,6-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataKi:  393nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290922(4-Phenyl-piperazine-1-carboxylic acid [4-methoxy-3...)
Affinity DataKi:  450nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290912(4-(2,4-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataKi:  571nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50173098(4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  700nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290916(4-o-Tolyl-piperazine-1-carboxylic acid 4-chloro-3-...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50084959(11'-Methyl-5-[[2'-methyl-4'-(5-methyl-1,2,4-oxadia...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290923(2-[4-Chloro-3-(4-methyl-piperazin-1-yl)-phenoxy]-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290919(4-(4-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataKi:  1.00E+3nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290913(2-[4-Methoxy-3-(4-methyl-piperazin-1-yl)-phenylami...)
Affinity DataKi:  3.00E+3nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290913(2-[4-Methoxy-3-(4-methyl-piperazin-1-yl)-phenylami...)
Affinity DataKi:  4.20E+4nMAssay Description:Affinity for 5-hydroxytryptamine 1D receptor subtypeMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataEC50:  2.10nMAssay Description:The compound was evaluated for intrinsic activity against human cloned 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290912(4-(2,4-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataEC50:  1.90nMAssay Description:The compound was evaluated for intrinsic activity against human cloned 5-hydroxytryptamine 1B receptor; full agonistMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290915(4-(2,6-Dimethyl-phenyl)-piperazine-1-carboxylic ac...)
Affinity DataEC50:  10nMAssay Description:The compound was evaluated for intrinsic activity against human cloned 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails Article