Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50032075
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich (Swiss Federal Institute Of Technology)

Curated by ChEMBL
LigandPNGBDBM50323923((E)-3-((2-(Fluoromethyl)thiazol-4-yl)ethynyl)cyclo...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich (Swiss Federal Institute Of Technology)

Curated by ChEMBL
LigandPNGBDBM50323924((E)-3-(Thiazol-2-ylethynyl)cyclohex-2-enone O-meth...)
Affinity DataKi:  20.3nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich (Swiss Federal Institute Of Technology)

Curated by ChEMBL
LigandPNGBDBM50323926((E)-3-((2-Methylthiazol-4-yl)ethynyl)cyclohex-2-en...)
Affinity DataKi:  21.9nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Eth Zurich (Swiss Federal Institute Of Technology)

Curated by ChEMBL
LigandPNGBDBM50323925((E)-3-(Thiazol-4-ylethynyl)cyclohex-2-enone O-2-(2...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebellum membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed