Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50032997
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337697((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337698((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human PKD3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337718(CHEMBL1683438 | N-(cyanomethyl)-3-(5-(4-((tetrahyd...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human PKD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337719(CHEMBL1683439 | N-(2-cyanopropan-2-yl)-3-(5-(4-((t...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337696((R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337695(3-(5-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-1H...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337720((S)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337713(CHEMBL1683433 | N-isopropyl-3-(5-(4-((isopropylami...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337705(CHEMBL1683423 | N-(cyanomethyl)-3-(5-(4-(4-methylp...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337711(CHEMBL1683430 | N-(cyanomethyl)-3-(5-(4-(4-methylp...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337704(CHEMBL1683422 | N-isopropyl-3-(5-(4-(4-methylpiper...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337717(CHEMBL1683437 | N-isopropyl-3-(5-(4-((tetrahydro-2...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337702(3-(5-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-1H...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337715(3-(5-(4-((cyclopropylamino)methyl)phenyl)-1H-pyraz...)
Affinity DataIC50:  390nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337714(CHEMBL1683311 | N-isopropyl-3-(5-(4-((2-methoxyeth...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337712((S)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337706(CHEMBL1683425 | N-(2-cyanoethyl)-3-(5-(4-(4-methyl...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337703(CHEMBL1683315 | N-isopropyl-3-(5-(6-(4-methylpiper...)
Affinity DataIC50:  980nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337701(CHEMBL1683313 | N-isopropyl-3-(5-(4-(4-methylpiper...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337710(3-(5-(4-(4-methylpiperazin-1-yl)phenyl)-1H-pyrazol...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337708(CHEMBL1683427 | N-(2-hydroxyethyl)-3-(5-(4-(4-meth...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337709(CHEMBL1683428 | N-(2-(dimethylamino)ethyl)-3-(5-(4...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337699(CHEMBL1683442 | N-(3-(5-(4-(4-methylpiperazin-1-yl...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337700(3-(5-(4-(4-methylpiperazin-1-yl)phenyl)-1H-pyrazol...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337716(CHEMBL1683434 | N-isopropyl-3-(5-(4-((2,2,2-triflu...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337707(CHEMBL1683426 | N-(2-methoxyethyl)-3-(5-(4-(4-meth...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)
Affinity DataIC50: >7.90E+3nMAssay Description:Inhibition of human CaMK2deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPkd1(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337695(3-(5-(3-bromo-4-(4-methylpiperazin-1-yl)phenyl)-1H...)
Affinity DataEC50:  680nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPkd1(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337696((R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)
Affinity DataEC50:  570nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPkd1(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337697((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)
Affinity DataEC50:  530nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPkd1(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337694((R)-N-(1-cyanoethyl)-3-(5-(4-((tetrahydro-2H-pyran...)
Affinity DataEC50:  240nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPkd1(Rattus norvegicus)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337698((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)
Affinity DataEC50:  460nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed