Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50034747
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281623(2-(4-fluorophenyl)-6-(2-naphthylsulfanyl)-1-hexana...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  4.10E+3nMAssay Description:Compound was tested for its ability to inhibit porcine pancreas phospholipase-A2More data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281621(6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281625(2-(4-fluorophenyl)-7-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281626(2-(4-fluorophenyl)-5-(2-naphthylsulfanyl)-1-pentan...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281623(2-(4-fluorophenyl)-6-(2-naphthylsulfanyl)-1-hexana...)
Affinity DataIC50:  1.45E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281621(6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281626(2-(4-fluorophenyl)-5-(2-naphthylsulfanyl)-1-pentan...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281624(2-(4-fluorophenyl)-5-(4-methylphenylsulfanyl)-1-pe...)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281624(2-(4-fluorophenyl)-5-(4-methylphenylsulfanyl)-1-pe...)
Affinity DataIC50:  2.83E+4nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281625(2-(4-fluorophenyl)-7-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281624(2-(4-fluorophenyl)-5-(4-methylphenylsulfanyl)-1-pe...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281624(2-(4-fluorophenyl)-5-(4-methylphenylsulfanyl)-1-pe...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281626(2-(4-fluorophenyl)-5-(2-naphthylsulfanyl)-1-pentan...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281625(2-(4-fluorophenyl)-7-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  4.87E+4nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281623(2-(4-fluorophenyl)-6-(2-naphthylsulfanyl)-1-hexana...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50015214(6-chloro-2-methoxy-9-acridinyl(4-diethylamino-1-me...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281624(2-(4-fluorophenyl)-5-(4-methylphenylsulfanyl)-1-pe...)
Affinity DataIC50:  1.97E+5nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Ovis aries (Sheep))
TBA

Curated by ChEMBL
LigandPNGBDBM50281624(2-(4-fluorophenyl)-5-(4-methylphenylsulfanyl)-1-pe...)
Affinity DataIC50:  2.15E+5nMAssay Description:Inhibition of ovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281621(6-[4-(tert-butyl)phenylsulfanyl]-2-(4-fluorophenyl...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin-H2 D-isomerase(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50281622(2-(4-fluorophenyl)-6-(4-methylphenylsulfanyl)-1-he...)
Affinity DataIC50:  2.80E+5nMAssay Description:Compound was tested for its ability to inhibit bovine seminal vesicle prostaglandin synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50: >7.50E+5nMAssay Description:Inhibitory activity against polymorphonuclear cell phospholipase-A2 in ratMore data for this Ligand-Target Pair
In DepthDetails Article