Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50037454
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151212(CHEMBL2368393 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151218(CHEMBL2368392 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151214(CHEMBL2368390 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151215(2-[6-(diethylamino)-3-(diethyliminiumyl)-3H-xanthe...)
Affinity DataKi:  54nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151216(CHEMBL2368391 | difluoro(2-{[(2Z)-1-methyl-5-{2-[(...)
Affinity DataKi:  55nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151213(CHEMBL365702 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[5...)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151219((2E)-2-[(2E)-3-[3,3-dimethyl-1-(5-{[2-(2-{2-[4-(2-...)
Affinity DataKi:  135nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151211(2,2-difluoro-12-[2-(methylcarbamoyl)ethyl]-4-(thio...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151217(CHEMBL2368394 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6...)
Affinity DataKd:  20nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151218(CHEMBL2368392 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[...)
Affinity DataKd:  4.10nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151213(CHEMBL365702 | difluoro(2-{[(2Z)-1-methyl-5-(2-{[5...)
Affinity DataKd:  14nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151212(CHEMBL2368393 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKd:  13nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151215(2-[6-(diethylamino)-3-(diethyliminiumyl)-3H-xanthe...)
Affinity DataKd:  19nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151219((2E)-2-[(2E)-3-[3,3-dimethyl-1-(5-{[2-(2-{2-[4-(2-...)
Affinity DataKd:  36nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151214(CHEMBL2368390 | difluoro(2-{[(2Z)-1-methyl-5-[2-({...)
Affinity DataKd:  22nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151216(CHEMBL2368391 | difluoro(2-{[(2Z)-1-methyl-5-{2-[(...)
Affinity DataKd:  13nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed