Compile Data Set for Download or QSAR
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Found 46 Enz. Inhib. hit(s) with all data for entry = 50004961
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50000041((+) (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-a...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030575(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030573(7-Methyl-8-oxo-5-phenyl-7,8-dihydro-[1,7]naphthyri...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030589(N-(3,5-bis(trifluoromethyl)benzyl)-N,7-dimethyl-8-...)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030576(4-(4-Fluoro-phenyl)-2-methyl-1-oxo-1,2-dihydro-iso...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030584(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030581(2-Methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030572(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030611(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030607(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030574(7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyr...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030591(6-Chloro-2-methyl-1-oxo-4-phenyl-1,2-dihydro-isoqu...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030569(1-(2-Chloro-benzyl)-1-methyl-3-(2,6,7-trimethyl-1-...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030582(7-Methyl-8-oxo-5-p-tolyl-7,8-dihydro-[1,7]naphthyr...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030585(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030594(2,6,7-Trimethyl-1-oxo-4-phenyl-1,2-dihydro-isoquin...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030604(3-[(2-Methoxy-benzylamino)-methyl]-2,6,7-trimethyl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030571(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030583(1-Benzyl-1-methyl-3-(2,6,7-trimethyl-1-oxo-4-pheny...)
Affinity DataIC50:  16nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030579(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030593(CHEMBL106326 | N-Methyl-N-(2-methyl-1-oxo-4-phenyl...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030598(1-(2-Methoxy-benzyl)-1-methyl-3-(2,6,7-trimethyl-1...)
Affinity DataIC50:  23nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030587(3-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-meth...)
Affinity DataIC50:  23nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030608(1-(3,5-Dimethyl-benzyl)-1-methyl-3-(2,6,7-trimethy...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030588(2-Methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030597(5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030606(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030578(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030601(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030577(1-(3,5-Bis-trifluoromethyl-benzyl)-1-methyl-3-(2,6...)
Affinity DataIC50:  54nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030580(1-Benzyl-1-ethyl-3-(2,6,7-trimethyl-1-oxo-4-phenyl...)
Affinity DataIC50:  66nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030605(CHEMBL326889 | N-(3,5-Bis-trifluoromethyl-benzyl)-...)
Affinity DataIC50:  68nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030610(2-(3,5-Bis-trifluoromethyl-phenyl)-N-methyl-N-(2-m...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030600(1-Benzyl-1-methyl-3-(2-methyl-1-oxo-4-phenyl-1,2-d...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030592(1-Benzyl-3-(2,6,7-trimethyl-1-oxo-4-phenyl-1,2-dih...)
Affinity DataIC50:  140nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030609(3-[(3,5-Bis-trifluoromethyl-benzylamino)-methyl]-2...)
Affinity DataIC50:  250nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030586(3-[(2-Methoxy-benzylamino)-methyl]-2-methyl-4-phen...)
Affinity DataIC50:  460nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030595(2-Methyl-1-oxo-4-o-tolyl-1,2-dihydro-isoquinoline-...)
Affinity DataIC50:  470nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030568(1-(2-Chloro-benzyl)-3-[4-(4-fluoro-phenyl)-2-methy...)
Affinity DataIC50:  480nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030596(3-{[(3,5-Bis-trifluoromethyl-benzyl)-methyl-amino]...)
Affinity DataIC50:  600nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030602(3-{[(2-Methoxy-benzyl)-methyl-amino]-methyl}-2,6,7...)
Affinity DataIC50:  800nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030599(1-m-Tolyl-3-(2,6,7-trimethyl-1-oxo-4-phenyl-1,2-di...)
Affinity DataIC50:  840nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030603(2-Methyl-1-oxo-4-phenyl-1,2-dihydro-isoquinoline-3...)
Affinity DataIC50:  860nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030590(1-Benzyl-3-[4-(4-fluoro-phenyl)-2-methyl-1-oxo-1,2...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50030570(1-Methyl-1-phenethyl-3-(2,6,7-trimethyl-1-oxo-4-ph...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of [125I]-BH-Substance P binding to tachykinin receptor 1 in human IM-9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed